HRI creates and preserves affordable homes and housing opportunities for all people, regardless of age, race, income, or identity. It provides comprehensive resident services and programming and develops innovative, replicable forms of affordable housing in order to provide the greatest range of housing options for low- and moderate-income households.

Stabilization is a 50 bed post-detox program providing intensive treatment and support for homeless men with histories of chronic substance misuse. Stabilization assists adult men (21 years or older) with successful recovery and reconnection to the community. The goal is to provide short-term clinical and support services, maximizing the potential for successful recovery, and providing the client with an understanding and acceptance of the need for continued treatment to prevent relapse. The program has the capacity to serve individuals who are dually diagnosed with a mental illness, as well as those living with HIV/AIDS or other chronic medical conditions. 

The newly expanded Southampton Street Shelter provides approximately 400 beds for homeless men aged 18 and over. Near to Boston Medical Center and run by the Boston Public Health Commission, it also offers a clinic for mental and physical health as well as case management for its residents. 

Woods Mullen is a women's only shelter in South Boston with 200 beds available 365 days a year, 24/7, for women aged 18 and over. Like the Southampton Street Shelter, it is run by the Boston Public Health Commission and offers meals, emergency clothing, connections to housing resources, and case management. 

Now part of Bay Cove Human Services, CASPAR provides community-based services for people with substance use disorders. CASPAR’s Emergency Services Center (ESC) shelter for homeless men and women provides life-saving services to 107 people nightly and over 1,000 unduplicated clients annually.  It is one of two shelters in Massachusetts that accept homeless people who are using drugs and alcohol. Guests receive medical and mental health care, nutritional food, personal hygiene supplies, clean clothes, counseling, case management, and employment, housing, and treatment referrals in an environment that is welcoming and safe.